JULÄINE® — Advanced Collagen Stimulating Injectable for Natural Rejuvenation

A New Era in Regenerative Anti‑Aging

JULÄINE® is a next‑generation collagen biostimulator that works with your body’s own biology to rebuild skin structure, improve firmness and restore youthful contours — without surgery. Unlike traditional dermal fillers that simply add volume, JULÄINE® activates your skin’s natural collagen production over time for subtle, long‑lasting rejuvenation.

BOOK NOW

 

 

What Is JULÄINE®?

JULÄINE® is an injectable treatment based on poly‑L‑lactic acid (PLLA), a biocompatible, biodegradable substance that stimulates collagen and elastin formation in the deeper dermal layers. Once injected, the high‑purity, uniform PLLA microspheres gradually activate fibroblasts — the skin’s repair cells — encouraging your body to rebuild its own natural support framework.

How Does It Work?

Unlike hyaluronic acid fillers that deliver instant but temporary volume, JULÄINE® works from within:

  1. Injection of PLLA Microspheres
    Fine injections are placed into the targeted areas using precise technique.

  2. Collagen Stimulation Over Time
    Over weeks and months, PLLA stimulates fibroblasts to produce new collagen and elastin fibres.

  3. Natural Skin Renewal
    As collagen rebuilds, skin becomes firmer, smoother, more elastic, and more youthful in appearance — without over‑filling.

Why Choose JULÄINE®?

Natural‑Looking, Long‑Lasting Results

Results develop gradually and progressively, creating a refreshed, lifted appearance rather than a “filled” look. With a series of treatments, effects can continue improving up to 12–24 months or more depending on your treatment plan.

Rebuilds Skin from Within

By encouraging your body to produce its own collagen and elastin, JULÄINE® strengthens your skin’s internal support network rather than simply masking ageing.

Versatile Rejuvenation

JULÄINE® can be used to address a range of concerns including:

  • Loss of facial volume

  • Fine lines and wrinkles

  • Skin laxity and sagging

  • Loss of firmness and elasticity

  • Texture irregularities

  • Neck and décolletage rejuvenation

Gradual & Understated

Because results unfold gradually over weeks, the outcome looks natural — your friends will notice your refreshed look without pinpointing why.

Perfect For

  • face lifting with collagen stimulation, suitable for Juliane treatment, North London

    LOWER FACE LIFTING

    JULÄINE® is a collagen biostimulator that revitalises the skin by encouraging natural collagen production. It restructures, rejuvenates, and tightens the lower face, providing a subtle lift with long-lasting, natural-looking results.

  • Juliane collagen stimulation for face and neck rejuvenation, London

    Face & Neck Rejuvenation

    JULÄINE® enhances overall skin quality by encouraging collagen and elastin formation. This helps restore firmness, reduce wrinkles, and improve skin texture, creating a rejuvenated and more youthful appearance.

  • cheek definition and lower face lifting using Juliane collagen biostimulator

    Cheek Lifting & Contouring

    JULÄINE® can also lift and define the mid-face. By stimulating collagen in the cheeks, it enhances natural contours and firmness, giving a subtle, refreshed look without over-filling or artificial volume.

Treatment Journey

  • patient consultation for Juliane treatment with Dr Marco Nicoloso, North London and Mayfair

    CONSULTATION

    All treatments are subject to a mandatory face to face consultation to determine suitability which includes medical history and a facial assessment. A personalised treatment plan will be agreed to target concerns and to reach the desired outcomes.

  • Juliane injection treatment being performed by Dr Marco Nicoloso for natural collagen stimulation

    TREATMENT

    Performing Julaine treatment requires an in depth knowledge of anatomy, a detailed facial examination and highly skilled and artistic eye to achieve natural looking results.

    Precision Injection – PLLA microspheres are carefully injected into target areas to stimulate collagen production.

    Gradual Collagen Activation – Over weeks, your body produces new collagen, firming and lifting the skin naturally.

  • post-treatment review and medical skincare advice following Juliane treatment, North London Muswell Hill

    REVIEW & SKINCARE

    Follow-Up & Maintenance – Most patients receive 2–3 sessions, spaced 4–6 weeks apart, for optimal results lasting 12–24 months

    As part of the consultation, a medical grade skin care regime is recommended to protect and improve skin quality in order to make the results of the treatment last longer.

BOOK NOW

  • JULÄINE® is a collagen-stimulating injectable (PLLA biostimulator) that gradually rebuilds your skin’s internal support network for natural, long-lasting rejuvenation.

  • JULÄINE® can improve the lower face, neck, cheeks, and overall skin quality, targeting laxity, wrinkles, and fine lines

  • Results appear gradually. Initial improvements may be seen within a few weeks, with full results developing over 8–12 weeks.

  • Typically 2–3 sessions, spaced 4–6 weeks apart, are recommended for optimal collagen stimulation and long-term improvement.

  • Results can last 12–24 months depending on skin condition, age, and maintenance plan.

  • Yes. JULÄINE® is biocompatible, biodegradable, and well-tolerated when administered by trained professionals. Mild swelling, redness, or tenderness may occur but usually resolves quickly.

  • Discomfort is minimal. Topical numbing or built-in anesthetic can be used for comfort during treatment.

  • Yes. JULÄINE® works well with fillers, botulinum toxin, or skin resurfacing treatments for comprehensive facial rejuvenation.

FREQUENTLY ASKED QUESTIONS

A woman in a light floral dress riding a bicycle through a park with trees and greenery.

The experience with Dr Marco at the clinic was great from start to finish. He is incredibly professional, and friendly, and took the time necessary to discuss my concerns, and understand my needs before starting treatment. I am very happy with my results, and would trust nobody else with my face! I have recommended him as well, and my friend is also happy with the results!

CLIENT TESTIMONIAL